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Psoriasis

Here you will find the latest clinical research on psoriasis.

Clinical Characteristics of Importance to Outcome in Patients With Spondyloarthritis

  Purpose The objective of the study is to investigate extra-articular manifestations, pain mechanisms, patient-reported outcomes, comorbidities and association between these conditions in patients with spondyloarthropathy (SpA) treated with Biologics. Further, to assess the predictive value of baseline pain profile on treatment outcome after ≥ 3 months. Condition Spondyloarthropathy Study …

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Korean College of Rheumatology Biologics Registry (KOBIO)

  Purpose We plan to establish a nationwide Biologics Registry (in the form of an inception cohort) to study the safety profiles in rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis patients receiving biologic agents.As this registry is to observe the “real world” use of anti-rheumatic treatments under routine clinical practice, …

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Psoriasis-Arthritis & Bone Program (PSARTROS)

  Purpose Purpose and rationale: To define the role of IL-17 as a mediator of structural bone lesions in psoriasis patients and patients with PsA. Primary Objective is the improvement of the PsAMRIS synovitis score baseline vs. week 24. Drug tested is Secukinumab 300 mg administered weekly for 4 weeks, …

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Use of Apremilast in Patients Who Are Dissatisfied With Stable Maintenance Topical Therapy

  Purpose Sixteen week open label study of apremilast in combination with topical steroids with a four week safety follow up visit. Condition Intervention Phase Plaque Psoriasis Drug: Apremilast Phase 4 Study Type: Interventional Study Design: Intervention Model: Single Group AssignmentMasking: None (Open Label)Primary Purpose: Treatment Official Title: Use of …

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Laser-assisted Topical Administration of Etanercept (Enbrel®) in Patients With Mild to Moderate Plaque-type Psoriasis

  Purpose The purpose of this study is to assess the feasibility and safety of topical administration of etanercept via AFL micropores to psoriatic plaques in patients with mild to moderate plaque-type psoriasis. While a wide variety of therapeutic innovations to treat moderate-to-severe psoriasis (accounting for around 30% of the …

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Pain Mechanisms and Ultrasonographic Disease Activity in Psoriatic Arthritis

  Purpose The objective of the study is to investigate pain mechanisms, ultrasonographic (US) inflammatory activity and association between these conditions in patients with psoriatic arthritis (PsA) intensifying anti-rheumatic treatment. Further, to assess the predictive value of baseline pain profile and US joint/entheses activity on treatment outcome after 4 months. …

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