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Psoriasis

Here you will find the latest clinical research on psoriasis.

Use of Apremilast in Patients Who Are Dissatisfied With Stable Maintenance Topical Therapy

  Purpose Sixteen week open label study of apremilast in combination with topical steroids with a four week safety follow up visit. Condition Intervention Phase Plaque Psoriasis Drug: Apremilast Phase 4 Study Type: Interventional Study Design: Intervention Model: Single Group AssignmentMasking: None (Open Label)Primary Purpose: Treatment Official Title: Use of …

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Laser-assisted Topical Administration of Etanercept (Enbrel®) in Patients With Mild to Moderate Plaque-type Psoriasis

  Purpose The purpose of this study is to assess the feasibility and safety of topical administration of etanercept via AFL micropores to psoriatic plaques in patients with mild to moderate plaque-type psoriasis. While a wide variety of therapeutic innovations to treat moderate-to-severe psoriasis (accounting for around 30% of the …

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Pain Mechanisms and Ultrasonographic Disease Activity in Psoriatic Arthritis

  Purpose The objective of the study is to investigate pain mechanisms, ultrasonographic (US) inflammatory activity and association between these conditions in patients with psoriatic arthritis (PsA) intensifying anti-rheumatic treatment. Further, to assess the predictive value of baseline pain profile and US joint/entheses activity on treatment outcome after 4 months. …

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Microneedle Patch for Psoriatic Plaques

  Purpose The purpose of this study is to evaluate the efficacy of microneedle patch on the psoriatic plaques. Condition Intervention Psoriasis Administration, Topical Device: Microneedle HA patch Device: Patch Other: Control Study Type: Interventional Study Design: Allocation: RandomizedIntervention Model: Parallel AssignmentMasking: Single (Outcomes Assessor)Primary Purpose: Treatment Official Title: Efficacy …

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The Effect of Riboflavin on Moderate to Severe Plaque Type Psoriasis

  Purpose The purpose of this study is to determine the anti-inflammatory effect of high-dose riboflavin supplementation on chronic plaque psoriasis. Psoriasis is a common chronic skin disorder that affects over 4 million people. There is no cure for psoriasis and treatment is directed at controlling patients’ symptoms. Amongst patients …

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Study of Efficacy and Safety of Secukinumab in Psoriatic Arthritis and Axial Spondyloarthritis Patients With Active Enthesitis Including One Achilles Tendon Site (ACHILLES)

  Purpose The purpose of this study is to demonstrate efficacy, including effects on inflammation by magnetic resonance imaging (MRI) assessments, of secukinumab on Achilles tendon enthesitis for up to 1 year with a primary focus at Week 24, in patients with active Psoriatic Arthritis and axial Spondyloarthritis despite current …

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An Open Label, Safety Study to Assess the Potential for Adrenal Suppression

  Purpose An Open Label, Safety Study to Assess the Potential for Adrenal Suppression Following Treatment with DSXS (Taro Pharmaceuticals U.S.A., Inc.) in Patients with Plaque Psoriasis Condition Intervention Phase Plaque Psoriasis Drug: DSXS topical Phase 2 Study Type: Interventional Study Design: Intervention Model: Single Group AssignmentMasking: None (Open Label)Primary …

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