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Longer TA repeat but not V89L polymorphisms in the SRD5A2 gene may confer acne risk in the Chinese population.

DOI: ada.2018.73162  PMCID: PMC5872244  PMID: 29610568   Several studies have reported that the V89L and TA repeat polymorphisms [(TA)n] of the SRD5A2 gene were associated with SRD5A2 activity. The activity of dihydrotestosterone, which is converted from testosterone by SRD5A2, is responsible for sebum secretion and the formation of acne. We hypothesized that abnormalities …

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An Acne Survey from the World’s Largest Annual Gathering of Twins.

PMID: 29601613   Surveying identical twins allows us to qualitatively separate genetic and environmental factors that may contribute to acne severity.To study a cohort of identical and fraternal twins to identify environmental factors that may influence acne severity.A survey was administered to 139 identical and fraternal twin multiples (279 subjects) at …

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