Recent Posts

Lipidomics reveals skin surface lipid abnormity in male youth acne.

DOI: bjd.16655  PMID: 29624645 Alterations of skin surface lipid (SSL) are believed to be one important factor of acne pathogenesis and SSL plays a key role in the initiation of the acne lesions. In this study, a powerful analytical technique, UPLC-QTOF-MS, was used to investigate the SSL variations of lipid main …

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Optimizing the use of topical retinoids in Asian acne patients.

DOI: 1346-8138.14314  PMID: 29611225   Acne vulgaris is a common disease among people in Asia. International guidelines and treatment recommendations emphasize the central role of topical retinoids in the management of acne. However, topical retinoids remain underutilized in clinical practise, which may be in part due to fear of retinoid-associated dermatitis/lack of …

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Longer TA repeat but not V89L polymorphisms in the SRD5A2 gene may confer acne risk in the Chinese population.

DOI: ada.2018.73162  PMCID: PMC5872244  PMID: 29610568   Several studies have reported that the V89L and TA repeat polymorphisms [(TA)n] of the SRD5A2 gene were associated with SRD5A2 activity. The activity of dihydrotestosterone, which is converted from testosterone by SRD5A2, is responsible for sebum secretion and the formation of acne. We hypothesized that abnormalities …

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