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Patch-testing with Plastics and Glues Series Allergens

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Abstract and Introduction Abstract Background: Few US studies have reported results of patch testing with plastics and glues.

Objective: To report our institution’s results of testing patients suspected of allergy to plastics and glues with a comprehensive plastics and glues series and to compare these results with previously published data.

Methods: Retrospective review of results of patch-testing with plastics and glues allergens at our institution between 2000 and 2007.

In total, 444 patients were patch-tested with up to 56 plastics and glues allergens in the specialized series and up to five plastics and glues allergens in a baseline series.

Positive-reaction rates were compared to other patch testing reports.

Results: Of patients, 97 (22%) had irritant reactions, and 201 (45%) had at least one allergic reaction.

Bis(2-dimethylaminoethyl) ether 1%, benzoyl peroxide 1%, epoxy resin, bisphenol F 0.

Testing with specialized series identified 193 patients with plastics and glues allergy, of whom 162 were not identified by testing with baseline series alone.

Conclusion: For patients suspected of allergy to plastics and glues, patch-testing with specialized series of plastics and glues allergens is an important adjunct to patch-testing with baseline series.

Introduction Plastics and Glues are macromolecular end products.

They are applied in a wide range of areas, including construction, packaging, electronics, recreation, and medicine.

Allergic contact dermatitis (ACD) from these materials is mostly attributed to nonpolymerized material that remains before the completion of a chemical reaction.

Therefore, most ACD from plastics and glues occurs in the occupational setting, especially in the manufacturing field.

Sources of non–occupation-related ACD include shoes and dental and medical devices such as dentures and hearing aids.

Plastics and glues can be classified into various categories, including epoxies, acrylics, polyurethanes, phenol-formaldehyde resins, and polyesters.

Although the medical literature describes the results of patch-testing with plastics and glues, information in the current literature is limited in regard to US rates of contact dermatitis from plastics and glues.

We present the results of patch-testing with plastics and glues at Mayo Clinic and compare them to results reported in the medical literature.

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