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Treatment of severe acne with isotretinoin in patients with inflammatory bowel disease.

PMID: 2147391  

Four patients with inflammatory bowel disease and severe cystic acne were treated with isotretinoin. Two patients had a successful course of treatment without any gastrointestinal side-effects. One patient had two episodes of profuse rectal bleeding that were probably related to pre-existing haemorrhoids. The fourth patient had a flare-up of his Crohn’s disease after starting isotretinoin.

Godfrey KM,  James MP

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