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The preadolescent acne microbiome: A prospective, randomized, pilot study investigating characterization and effects of acne therapy.

DOI: pde.13261  PMID: 29024079  

Acne, a common pediatric disease, tends to be more comedonal in preadolescents, whereas older individuals are more likely to have inflammatory lesions in addition to comedones. Thus the microbiome of preadolescents may be different. In this pilot study we aimed to characterize the preadolescent acne microbiome, compare the microbiome in preadolescents with and without acne, and investigate changes in the microbiome after topical treatment with benzoyl peroxide or a retinoid in a small cohort of preadolescents.

Coughlin CC,  Swink SM,  Horwinski J,  Sfyroera G,  Bugayev J,  Grice EA,  Yan AC

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