Home / Acne / Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) Syndrome with Significant Bilateral Pleural Effusions.

Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) Syndrome with Significant Bilateral Pleural Effusions.

DOI: internalmedicine.8250-16  PMID: 28924111  

We herein report a rare case of a 66-year-old woman who had synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome with marked sternal osteitis and bilateral pleural effusions. SAPHO syndrome was diagnosed based on the characteristic features of a hyperostotic sternum and thoracic spine. The inflammatory changes of sternal osteitis and involvement of the adjacent soft tissue were assumed to be the cause of the pleural effusions. The effusions decreased during the natural course of the disease and resolved after methotrexate therapy. The pain dramatically decreased with oral tramadol. Physicians should consider the possibility of SAPHO syndrome in patients with anterior chest pain and pleural effusions.

Hasegawa S,  Yabe H,  Kaneko N,  Watanabe E,  Gono T,  Terai C

About

Check Also

A cross-sectional study of clinical factors associated with acne facial scarring in patients with active acne.

DOI: jdv.14726  PMID: 29194788   Scarring may occur in 45% to 55% of acne patients, it may …

Leave a Reply

Your email address will not be published. Required fields are marked *