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Acne

Case Reports of Acne and Homeopathy.

DOI: 000486309  PMID: 29490312   Acne vulgaris is a self-limiting disorder of the pilosebaceous unit. The aesthetic aspect of the disorder may provoke depression and diminish the quality of life. A number of agents are used for acne treatment, e.g., retinoids, antibiotics, benzoic acid, azelaic acid, and hormones. These agents have side-effects, sometimes severe ones.Presented are 2 …

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Clinical and histopathological characteristics in patients with scarring folliculitis type of acne inversa.

DOI: 19381980.2017.1361575  PMCID: PMC5821155  PMID: 29484097   Objective: This study was designed to study the clinical and histopathological characteristics of patients with the scarring folliculitis type acne inversa in Chinese population. Methods: A total of 21 patients with acne inversa and 6 controls without known dermatological disease were recruited from outpatient department of …

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Cleanser use could decrease numbers of Demodex Folliculorum in mild to moderate acne patients.

DOI: 19381980.2017.1348444  PMCID: PMC5821153  PMID: 29485142   Objective: This study was to verify if the skin cleanser could help decrease the infection ratio of Demodex Folliculorum in acne patients. Methods: 132 participants with mild to moderate vulgaris acne participated in this monocentric, prospective, double-blind study. Dermatologists grading and Standardized Skin Surface Biopsy were …

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The effect on acne quality of life of topical azelaic acid 15% gel versus a combined oral contraceptive in adult female acne: A randomized trial.

DOI: 19381980.2017.1361572  PMCID: PMC5821159  PMID: 29484094   Acne vulgaris is a chronic inflammatory disease that affects the pilosebaceous unit. Recent studies have shown an increasing number of cases of acne in adult women. These cases are predominantly normoandrogenic and have show some clinical differences compared to adolescent acne. In addition to the physical …

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Special types of folliculitis which should be differentiated from acne.

DOI: 19381980.2017.1356519  PMCID: PMC5821164  PMID: 29484091   Because both acne vulgaris and folliculitis can present as inflammatory erythematous papules, pustules or nodules, they are often hard to distinguish. The importance to distinguish between these 2 shall be stressed as their pathogenesis and therapies are different and misdiagnosis or missed diagnosis may lead to …

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Seeking new acne treatment from natural products, devices and synthetic drug discovery.

DOI: 19381980.2017.1356520  PMCID: PMC5821150  PMID: 29484092   Despite lots of research on the pathogenesis of acne, the development of new therapeutic agents is still stagnant. Conventional agents which target multiple pathological processes have some serious side effects and this makes seeking new treatment options important for treating acne. As new therapeutic options, researchers …

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Modulation of Toll Like Receptor-2 on sebaceous gland by the treatment of adult female acne.

DOI: 19381980.2017.1361570  PMCID: PMC5821154  PMID: 29484093   Adult female acne is a chronic inflammatory, immune-mediated disease that affects the pilosebaceous unit in women in their 20s to 40s, and is considered different from acne vulgaris. Propionibacterium acnes is recognized by TLR-2, resulting in activation of this receptor and an inflammatory response through the …

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RIS-1/psoriasin expression in epithelial skin cells indicates their selective role in innate immunity and in inflammatory skin diseases including acne.

DOI: 19381980.2017.1338993  PMCID: PMC5821165  PMID: 29484089   RIS-1/psoriasin/S100A7 is an epithelial antimicrobial peptide, whose expression is upregulated in inflammatory skin diseases and is induced by retinoids. Its molecular expression was investigated in skin cell cultures and in skin specimens to better understand its role in inflammatory procedures of the pilosebaceous unit.rtPCR and northern …

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Dermatological indications for the use of isotretinoin beyond acne.

DOI: 09546634.2018.1445194  PMID: 29480033   Whilst the use of isotretinoin has revolutionized the treatment of acne vulgaris, isotretinoin is increasingly recognized as a useful therapeutic option for many other cutaneous conditions. We review the evidence underlying the use of isotretinoin for a variety of dermatological indications including hidradenitis suppurativa, sebaceous gland pathology, …

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Clinical significance of neutrophil gelatinase-associated lipocalin and galectin-7 in tape-stripped stratum corneum of acne vulgaris.

DOI: 1346-8138.14261  PMID: 29473202   The usefulness of stratum corneum neutrophil gelatinase-associated lipocalin and stratum corneum galectin-7 as biomarkers of acne vulgaris was studied. A comparison of neutrophil gelatinase-associated lipocalin levels on the cheeks of patients with acne vulgaris at the start of the study and at the time of symptom improvement …

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