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Patients with dermatitis herpetiformis, acne, psoriasis and Darier’s disease have low epidermal zinc concentrations.

PMID: 1977254   Zinc concentration was determined in epidermis, papillary dermis and serum in patients with dermatitis herpetiformis, acne or psoriasis and in two small groups of patients with ichthyosis vulgaris and Darier’s disease. Except in ichthyosis vulgaris the zinc level in epidermis was decreased in all these disorders. The mean …

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Isotretinoin therapy for acne vulgaris: results in an Irish population.

PMID: 2138592   The results of treatment of cystic and antibiotic-resistant acne vulgaris in 96 consecutive patients with the oral retinoid isotretinoin (13-cis-retinoic acid; Roacentane) are reported retrospectively. The results show that the drug, while toxic in the short term, is highly effective in clearing acne. Buckley D,  Rogers S,  Daly P

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The pathogenesis and treatment of acne.

DOI: annurev.me.41.020190.001155  PMID: 2139553   Acne is a follicular disorder of the skin occurring in specialized pilosebaceous units on the face and trunk. An abnormality of the keratinizing epithelium of these follicles, thought to be due to the action of sebum synthesized and secreted by the androgen-sensitive sebaceous glands, leads to inflammation …

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Late onset adrenal hyperplasia in a group of Irish females who presented with hirsutism, irregular menses and/or cystic acne.

PMID: 2139596   The aims of this study were to determine the frequency of late-onset adrenal hyperplasia due specifically to 21-hydroxylase deficiency in a group of Irish women who presented at a Dublin Clinic with symptoms of hyperandrogenism, including hirsutism, menstrual irregularities and/or cystic acne, and to determine if those with …

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