DOI: jamadermatol.2018.0110 PMID: 29541753 Are light therapies effective and safe for treating acne?The evidence for all light therapies remains weak and inconclusive. Red-light methyl aminolevulinate-photodynamic therapy (MAL-PDT) was the only treatment associated with a small though clinically insignificant reduction in the number of inflamed lesions and in global improvement as assessed by an investigator in moderate …Read More »
Efficacy and Safety of Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel Plus Oral Doxycycline in Subjects With Severe Inflammatory Acne Who Are Candidates for Oral Isotretinoin.
PMID: 29537444 Acne treatment guidelines suggest a combination approach with topical therapy including a topical retinoid, benzoyl peroxide and an oral antibiotic, or oral isotretinoin (OI), as first-line treatment options for severe acne vulgaris (AV). This study evaluated the efficacy and safety of a daily regimen of 0.3% adapalene and …Read More »
Efficacy and Safety of Sarecycline, a Novel, Once-Daily, Narrow Spectrum Antibiotic for the Treatment of Moderate to Severe Facial Acne Vulgaris: Results of a Phase 2, Dose-Ranging Study.
PMID: 29537451 There is a need for new oral antibiotics for acne with improved safety profiles and targeted antibacterial spectra. Sarecycline is a novel, tetracycline-class antibiotic specifically designed for acne, offering a narrow spectrum of activity compared with currently available tetracyclines, including less activity against enteric Gram-negative bacteria. This phase …Read More »
DOI: 09273948.2018.1433305 PMID: 29533687 To evaluate the results of tear functions in acne rosacea.This prospective study includes 64 eyes of 32 acne rosacea patients without blepharitis and meibomian gland dysfunction and 90 eyes of 45 patients as control group. Tear functions of all were evaluated with ocular surface disease index (OSDI) …Read More »
DOI: jocd.12523 PMID: 29524284 A comprehensive study comparing two different modalities, Nokor needle subcision (NNS) and blunt cannula subcision (BCS), for treatment of acne scars, has not been reported previously. The aim was to compare the effectiveness of these two methods based on patient’s and doctor’s satisfaction measures, in addition to …Read More »
Validation of 3D skin imaging for objective repeatable quantification of severity of atrophic acne scarring.
DOI: srt.12464 PMID: 29512189 One major sequelae of acne is atrophic scarring, yet objective tools to assess scars are lacking. Neither depth nor volume of atrophic scars is readily evaluable clinically and standard 2D photography is significantly affected by lighting and shadows. The aim of our study was to define and …Read More »
DOI: 19381980.2017.1361571 PMCID: PMC5823034 PMID: 29497466 Acne vulgaris is a chronic inflammatory disease that affects the pilosebaceous unit. Recent studies have shown an increasing number of cases of acne in adult women. These cases are predominantly normoandrogenic and present some clinical differences compared to adolescent acne. Local glandular metabolism turns some weak …Read More »
IL1A (-889) gene polymorphism is associated with the effect of diet as a risk factor in Acne Vulgaris.
DOI: jocd.12516 PMID: 29498183 Despite the several studies suggesting the genetic basis of acne vulgaris, the exact genetic architecture of this very common condition is not yet clear.This study aimed to investigate the association between IL-1A (-889) gene polymorphism and acne vulgaris in a sample of patients.Blood samples from 100 patients …Read More »
DOI: 1078155218761799 PMID: 29498323 Imatinib mesylate is a tyrosine kinase inhibitor used in the treatment of several malignancies. Its use, however, is associated with a number of toxic effects including adverse cutaneous reactions. Herein, we present a case of facial cystic acne in a patient receiving imatinib therapy for chronic myelocytic …Read More »
The Role of the Physician in Patient Perceptions of Barriers to Primary Adherence With Acne Medications.
DOI: jamadermatol.2017.6144 PMID: 29490358 Primary nonadherence with acne medications is high but commonly underreported to prescribing physicians.To describe patient experiences with primary nonadherence to medications for acne and to identify physician-level factors that may improve adherence in this population.A qualitative analysis was conducted from structured interviews with patients reporting nonadherence with …Read More »