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Light Therapies for Acne.

DOI: jamadermatol.2018.0110  PMID: 29541753   Are light therapies effective and safe for treating acne?The evidence for all light therapies remains weak and inconclusive. Red-light methyl aminolevulinate-photodynamic therapy (MAL-PDT) was the only treatment associated with a small though clinically insignificant reduction in the number of inflamed lesions and in global improvement as assessed by an investigator in moderate …

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Efficacy and Safety of Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel Plus Oral Doxycycline in Subjects With Severe Inflammatory Acne Who Are Candidates for Oral Isotretinoin.

PMID: 29537444   Acne treatment guidelines suggest a combination approach with topical therapy including a topical retinoid, benzoyl peroxide and an oral antibiotic, or oral isotretinoin (OI), as first-line treatment options for severe acne vulgaris (AV). This study evaluated the efficacy and safety of a daily regimen of 0.3% adapalene and …

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Efficacy and Safety of Sarecycline, a Novel, Once-Daily, Narrow Spectrum Antibiotic for the Treatment of Moderate to Severe Facial Acne Vulgaris: Results of a Phase 2, Dose-Ranging Study.

PMID: 29537451   There is a need for new oral antibiotics for acne with improved safety profiles and targeted antibacterial spectra. Sarecycline is a novel, tetracycline-class antibiotic specifically designed for acne, offering a narrow spectrum of activity compared with currently available tetracyclines, including less activity against enteric Gram-negative bacteria. This phase …

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ADT-G as a promising biomarker for peripheral hyperandrogenism in adult female acne.

DOI: 19381980.2017.1361571  PMCID: PMC5823034  PMID: 29497466   Acne vulgaris is a chronic inflammatory disease that affects the pilosebaceous unit. Recent studies have shown an increasing number of cases of acne in adult women. These cases are predominantly normoandrogenic and present some clinical differences compared to adolescent acne. Local glandular metabolism turns some weak …

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Cystic acne due to imatinib therapy for chronic myelocytic leukemia.

DOI: 1078155218761799  PMID: 29498323   Imatinib mesylate is a tyrosine kinase inhibitor used in the treatment of several malignancies. Its use, however, is associated with a number of toxic effects including adverse cutaneous reactions. Herein, we present a case of facial cystic acne in a patient receiving imatinib therapy for chronic myelocytic …

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The Role of the Physician in Patient Perceptions of Barriers to Primary Adherence With Acne Medications.

DOI: jamadermatol.2017.6144  PMID: 29490358   Primary nonadherence with acne medications is high but commonly underreported to prescribing physicians.To describe patient experiences with primary nonadherence to medications for acne and to identify physician-level factors that may improve adherence in this population.A qualitative analysis was conducted from structured interviews with patients reporting nonadherence with …

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