PMID: 2138493 Twenty-five previously untreated acne patients were monitored throughout a 6-month course of therapy with either tetracycline or minocycline for changes in the numbers of staphylococci, propionibacteria and yeasts of the genus Malessezia on the skin surface. Antibiotic resistant staphylococci and propionibacteria were also counted. Minocycline (50 mg b.d.) …Read More »
PMID: 2143182 Acharya SRRead More »
PMID: 2151863Read More »
PMID: 2137846 Acne is known to be one of the features of hyperandrogenism. The aim of the present work was to study women with persistent acne and without other evidence of hyperandrogenism, such as hirsutism, alopecia, or irregular menses. Among 87 female patients with acne and/or hirsutism, we defined three …Read More »
PMID: 2139236 Amblard PRead More »
A placebo-controlled study to evaluate the efficacy of topical tetracycline and oral tetracycline in the treatment of mild to moderate acne. Dermatology Research Group.
DOI: 030006059001800204 PMID: 2140332 This double-blind, parallel group multicentre study in 85 hospital out-patients with mild to moderate acne evaluated the efficacy of 2.2 mg/ml topical tetracycline or placebo applied twice daily for 16 weeks together with an initial course of oral tetracycline, at doses of 1000 mg/day during weeks 1-4 …Read More »
PMID: 2147165 Datta PK, Saha SSRead More »
Isotretinoin treatment of severe acne affects the endogenous concentration of vitamin A in sebaceous glands.
PMID: 2138202 An investigation of pooled skin samples from 22 acne patients has shown that isotretinoin and its major metabolite, 4-oxo-isotretinoin, can be detected in sebaceous glands during treatment with isotretinoin (1 mg/kg/d for 4 months). The levels are less than those in the epidermis, thus excluding selective drug distribution …Read More »
PMID: 2138639Read More »
PMID: 2138640 Bunker CB, Rustin MH, Dowd PMRead More »