DOI: pde.13448 PMID: 29575091 We describe the difficulties of treating acne in a series of female-to-male transgender adolescents, including concerns about potential hepatotoxicity with concomitant use of testosterone with isotretinoin or tetracyclines. Acne is a foreseeable adverse effect of testosterone treatment in transgender adolescents, so monitoring for acne is advised. The treatment of acne in transgender …Read More »
Th17/Treg imbalance in hidradentitis suppurativa/acne inversa: the link to hair follicle dissection, obesity, smoking, and autoimmune comorbidities.
DOI: bjd.16561 PMID: 29573406 Disintegration of the infundibula of terminal hair follicles (HF) in intertriginous skin areas exhibits the histological hallmark of hidradenitis suppurativa (HS)/acne inversa, featuring a dissecting terminal hair folliculitis. Elevated serum levels of interleukin 17 and local increase in the ratio of proinflammatory Th17 cells and antiinflammatory regulatory …Read More »
DOI: jdv.14948 PMID: 29573483 Acne is a common chronic skin disease with a multifactorial etiology and pathogenesis. Recently, circular RNAs (circRNAs) have been identified as a key factor in regulating gene expression through circRNA-miRNA-mRNA networks in many biological processes and human diseases. However, the circRNAs expression in patients with acne is …Read More »
Reducing the oral isotretinoin skin side effects: efficacy of 8% omega-ceramides, hydrophilic sugars, 5% niacinamide cream compound in acne patients.
DOI: S0392-0488.17.05742-X PMID: 29564872 Acne vulgaris is a chronic inflammatory skin disease that manifests as open and closed comedones as well as inflammatory papules, pustules, and nodules localized on face and trunk. Oral isotretinoin demonstrated to be effective in controlling seborrhea, inflammation, Propionibacterium Acnes hyperproliferation and reducing scarring, nevertheless muco-cutaneous side …Read More »
The Use of Hormonal Antiandrogen Therapy in Female Patients with Acne: A 10-Year Retrospective Study.
DOI: s40257-018-0349-6 PMID: 29556985 Little is known about how dermatologists prescribe hormonal antiandrogen acne treatment (HAAT).The aim of this study was to investigate dermatologists’ HAAT-prescribing habits and HAAT’s impact on systemic antibiotic use in women with acne.We performed a retrospective study at an academic medical center of female patients receiving HAAT …Read More »
‘Disease, illness, affliction? Don’t know’: Ambivalence and ambiguity in the narratives of young people about having acne.
DOI: 1363459318762035 PMID: 29552892 The popular characterisation of acne as a mundane and insignificant feature of adolescence sits at odds with academic studies showing the detrimental impacts of the condition on people of various ages. Drawing from in-depth qualitative interviews with 13- to 25-year olds living in England, this article will …Read More »
DOI: j.jid.2018.02.038 PMID: 29548797 Our understanding of the microbiome and the role of P. acnes in skin homeostasis and acne pathogenesis is evolving. Multiple methods for sampling and identifying the skin’s microbiome exist and understanding the differences between the abilities of various methods to characterize the microbial landscape is warranted. This …Read More »
Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison.
DOI: s40257-018-0352-y PMID: 29549588 Very few clinical trials have investigated the effect of topical acne treatment on scarring.Our objective was to evaluate the efficacy of adapalene 0.3%/benzoyl peroxide 2.5% gel (A0.3/BPO2.5) in atrophic acne scar formation in patients with acne.In this multicenter, randomized, investigator-blinded, vehicle-controlled study, subjects with moderate or severe …Read More »
DOI: s13555-018-0231-8 PMID: 29549598 Scarring is an unfortunate clinical outcome of acne. Current treatment options for atrophic acne scars are dominated by non-pharmacological, invasive procedures which may not be suitable or affordable to all patients. This phase II, single-center, open-label, exploratory study assessed the efficacy, safety and subject-reported outcomes of adapalene …Read More »
DOI: jocd.12520 PMID: 29543377 Acne is very common skin condition. Most patients with acne will have a degree of scarring as a result of their acne. In patients with darker skin color the scarring can be further complicated by hyperpigmentation. Several treatment options can be used to improve acne scarring, however …Read More »