Home / Acne / Letter to the Editor submitted in response to “The Extinction of Topical Erythromycin Therapy for Acne Vulgaris and Concern for the Future of Topical Clindamycin.”

Letter to the Editor submitted in response to “The Extinction of Topical Erythromycin Therapy for Acne Vulgaris and Concern for the Future of Topical Clindamycin.”

DOI: 09546634.2017.1335852  PMID: 28545314  

Gupta T,  Sardana K,  Kumar B,  Gautam HK

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Longer TA repeat but not V89L polymorphisms in the SRD5A2 gene may confer acne risk in the Chinese population.

DOI: ada.2018.73162  PMCID: PMC5872244  PMID: 29610568   Several studies have reported that the V89L and TA repeat polymorphisms [(TA)n] of the SRD5A2 gene were associated with SRD5A2 activity. The activity of dihydrotestosterone, which is converted from testosterone by SRD5A2, is responsible for sebum secretion and the formation of acne. We hypothesized that abnormalities in SRD5A2 action could contribute …

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