Home / Acne / Isotretinoin-induced acne fulminans without systemic symptoms with concurrent exuberant granulation tissue.

Isotretinoin-induced acne fulminans without systemic symptoms with concurrent exuberant granulation tissue.

DOI: pde.13389  PMID: 29314240  

Acne fulminans is a severe form of acne characterized by painful, inflammatory nodules that progress into ulcers and concurrent systemic symptoms. Treatment of acne with isotretinoin can precipitate a syndrome called isotretinoin-induced acne fulminans without systemic symptoms. An exuberant granulation tissue response, another known adverse event associated with isotretinoin, can occur concurrently, inhibiting wound repair and complicating treatment. We report a case of isotretinoin-induced acne fulminans without systemic symptoms with exuberant granulation tissue response that was treated successfully with topical clobetasol ointment.

Li AW,  Antaya RJ

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