The effectiveness and tolerance of isotretinoin have been assessed in 72 cases (34 male and 38 female) suffering from papulo-pustular acne with nodulo-cystic component recalcitrant to traditional treatments. The drug confirmed its noteworthy effectiveness and speed of action in all cases. Stress is laid in particular on the lack of recurrence even after a very long-term follow-up. Tolerance was also very good with a prevalent incidence of mucocutaneous signs (desquamation, cheilitis, dermatitis) and the consequent acceptability of treatment on the part of patients.
Scaglione R, Desirello G, Pazzaglia A