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Current views on the aetiology, pathogenesis and treatment of acne vulgaris.

PMID: 2141311  

Acne may vary from a relatively trivial condition to a severe disfiguring disease and management must be tailored to suit individuals. Pathogenetic factors that may be addressed by treatment include increased sebum secretion, abnormal follicular keratinisation, bacterial colonisation and local inflammation. Mild acne can be controlled with topical preparations alone but many patients with more severe disease require oral therapy with antibiotics, antiandrogens or retinoids. Combinations of topical and systemic treatments are often appropriate. The choice of drug requires knowledge of their efficacy, ease of use and possible adverse effects.

Lever L,  Marks R

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DOI: 1346-8138.14314  PMID: 29611225   Acne vulgaris is a common disease among people in Asia. International guidelines and treatment recommendations emphasize the central role of topical retinoids in the management of acne. However, topical retinoids remain underutilized in clinical practise, which may be in part due to fear of retinoid-associated dermatitis/lack of experience, particularly in Asian patients. …

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