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Caution is key when prescribing spironolactone for adult acne



NEWPORT BEACH, CALIF. – While off-label use of spironolactone for the treatment of acne is quite common, it should be prescribed with special caution, advised Julie C. Harper, MD.

he offered this blunt advice about one potential patient group: “Do not use this in men.” She cited a 2006 Japanese study of 139 patients with acne, treated with oral spironolactone, which found that 3 of the 23 males in the study developed gynecomastia within 4-6 weeks. Subsequently, the treatment was stopped in all male patients (Aesthetic Plast Surg. 2006 Nov-Dec;30[6]:689-94).

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Dr Kim developed (and is continuing to develop) dermatology research news as we way from dermatologists to stay on top of the latest advances in the field of dermatology.

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