A pilot study recently published in the Journal of Drugs in Dermatology shows that a combination of salicylic acid and botanical extracts can reduce erythema associated with mild acne.
Researchers combined an over-the-counter topical gel containing 2 percent salicylic acid combined with botanicals that have been known to have anti-inflammatory properties.
This was a proof-of-concept randomized, blinded, split-face study whose goal was to determine if this formulation could reduce the redness, elevation and induration associated with acne lesions. It included 25 patients who, after 10 days, reported having a 15-20 percent reduction in redness consistently over the course of the study.
Typical commercial over-the-counter products are based on benzoyl peroxide and salicylic acid, both of which are effective in reducing lesions, but neither have the capability to immediately reduce inflammation or redness. In addition, benzoyl peroxide is poorly tolerated by some patients and is associated with skin irritation and allergic contact dermatitis, the authors wrote.
In this study, researchers evaluated Kamedis Acne Spot Treatment (Kamedis Ltd), which includes 10 percent herbal botanical ingredients associated with having antibacterial, antioxidant and anti-inflammatory properties. Those ingredients included Rheum palmatum, Portulaca oleracea, Chrysanthemum indicum, Scutullaria baicalensis, Phellodendron amurense, Sanguisorba officinalis and Sapindus mukorossi.Full Article