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Clinical evidence for washing and cleansers in acne vulgaris: A systematic review.

DOI: 09546634.2018.1442552  PMID: 29460655   Washing and over-the-counter cleansers are common interventions in acne vulgaris (AV), but the clinical evidence for their benefit is poorly understood. This systematic review presents clinical studies of washing and cleanser efficacy in acne vulgaris to guide treatment recommendations of dermatologists.We surveyed English-language articles indexed in MEDLINE …

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Pyoderma gangrenosum, acne, and suppurative hidradenitis syndrome in end-stage renal disease successfully treated with adalimumab.

PMID: 29447652   PASH syndrome (pyoderma gangrenosum, acne, and suppurative hidradenitis) forms part of the spectrum of autoinflammatory diseases. We report an unusual case of PASH syndrome in a patient with end-stagerenal disease (ESRD) who was successfully treated with the tumor necrosis factor inhibitor, adalimumab. The case underscores the challenges associatedwith …

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The efficacy and safety of non-pharmacological therapies for the treatment of acne vulgaris: A systematic review and best-evidence synthesis.

DOI: jdv.14881  PMID: 29444375   Acne vulgaris is a multifaceted skin disorder, affecting more than 85% of young individuals worldwide. Pharmacological therapy is not always desirable because of the development of antibiotic resistance or the potential risk of adverse effects. Non-pharmacological therapies can be viable alternatives for conventional therapies. However, sufficient evidence …

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Adult-onset acne: prevalence, impact, and management challenges.

DOI: CCID.S137794  PMCID: PMC5798558  PMID: 29440921   Acne is a multifactorial and inflammatory disease of pilosebaceous follicles, which affects most adolescents. Recent epidemiological data revealed a difference in adults affected by this disease. Women have a high prevalence and incidence when compared with men, especially after 25 years of age. In contrast to …

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Formulation And In-Vitro And Ex-Vivo Evaluation Of Tretinoin Loaded Cubosomal Gel For Acne Treatment.

DOI: 1872211312666180213121117  PMID: 29437029   The current work was attempted to formulate and evaluate the topical sustained release delivery systems potential of bicontinuous cubic monoglyceride -water phases – ‘cubosomes’ containing Tretinoin with an opinion to sustain the release of drug in the acne treatment.Tretinoin loaded cubosomes were prepared by bottom-up technique, by …

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A Qualitative Investigation of the Impact of Acne on Health-Related Quality of Life (HRQL): Development of a Conceptual Model.

DOI: s13555-018-0224-7  PMID: 29435857   The negative impact of acne on aspects of health-related quality of life (HRQL) has been demonstrated in many quantitative studies; however, there has been relatively little qualitative research exploring the impact of acne and the use of topical treatment. The study aimed to explore the impact of …

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Topical Delivery of Erythromycin Through Cubosomes For Acne.

DOI: 2211738506666180209100222  PMID: 29424323   Topical delivery is an attractive route for local and systemic treatment. Novel topical application has many advantages like avoids the GI-irritation, prevent the metabolism of drug in the liver and increase the bioavailability of the drug over the conventional dosage forms. The aim of present work was …

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