PMID: 29447630 The purpose of this literature review is to evaluate the use of metformin as an adjunct therapy in the treatment of moderate-to-severe acne in those not diagnosed with polycystic ovary syndrome (PCOS) or androgen excess. The authors conducted independent literature searches. Results were limited to clinical trials and …Read More »
Pyoderma gangrenosum, acne, and suppurative hidradenitis syndrome in end-stage renal disease successfully treated with adalimumab.
PMID: 29447652 PASH syndrome (pyoderma gangrenosum, acne, and suppurative hidradenitis) forms part of the spectrum of autoinflammatory diseases. We report an unusual case of PASH syndrome in a patient with end-stagerenal disease (ESRD) who was successfully treated with the tumor necrosis factor inhibitor, adalimumab. The case underscores the challenges associatedwith …Read More »
The efficacy and safety of non-pharmacological therapies for the treatment of acne vulgaris: A systematic review and best-evidence synthesis.
DOI: jdv.14881 PMID: 29444375 Acne vulgaris is a multifaceted skin disorder, affecting more than 85% of young individuals worldwide. Pharmacological therapy is not always desirable because of the development of antibiotic resistance or the potential risk of adverse effects. Non-pharmacological therapies can be viable alternatives for conventional therapies. However, sufficient evidence …Read More »
DOI: CCID.S137794 PMCID: PMC5798558 PMID: 29440921 Acne is a multifactorial and inflammatory disease of pilosebaceous follicles, which affects most adolescents. Recent epidemiological data revealed a difference in adults affected by this disease. Women have a high prevalence and incidence when compared with men, especially after 25 years of age. In contrast to …Read More »
Formulation And In-Vitro And Ex-Vivo Evaluation Of Tretinoin Loaded Cubosomal Gel For Acne Treatment.
DOI: 1872211312666180213121117 PMID: 29437029 The current work was attempted to formulate and evaluate the topical sustained release delivery systems potential of bicontinuous cubic monoglyceride -water phases – ‘cubosomes’ containing Tretinoin with an opinion to sustain the release of drug in the acne treatment.Tretinoin loaded cubosomes were prepared by bottom-up technique, by …Read More »
A Qualitative Investigation of the Impact of Acne on Health-Related Quality of Life (HRQL): Development of a Conceptual Model.
DOI: s13555-018-0224-7 PMID: 29435857 The negative impact of acne on aspects of health-related quality of life (HRQL) has been demonstrated in many quantitative studies; however, there has been relatively little qualitative research exploring the impact of acne and the use of topical treatment. The study aimed to explore the impact of …Read More »
DOI: 2211738506666180209100222 PMID: 29424323 Topical delivery is an attractive route for local and systemic treatment. Novel topical application has many advantages like avoids the GI-irritation, prevent the metabolism of drug in the liver and increase the bioavailability of the drug over the conventional dosage forms. The aim of present work was …Read More »
Efficacy of Intense-pulsed Light Therapy with Topical Benzoyl Peroxide 5% versus Benzoyl Peroxide 5% Alone in Mild-to-moderate Acne Vulgaris: A Randomized Controlled Trial.
DOI: jrpp.JRPP_17_29 PMCID: PMC5787904 PMID: 29417078 Acne vulgaris is a disease of pilosebaceous unit with multifactorial pathogenesis and threats patients’ social functioning. There is a growing research to find faster, more effective, and easy to use treatments. The aim of this study is to evaluate the efficacy of benzoyl peroxide 5% (BP) …Read More »
Comparing the Efficacy of Low Dose and Conventional Dose of Oral Isotretinoin in Treatment of Moderate and Severe Acne Vulgaris.
DOI: jrpp.JRPP_17_30 PMCID: PMC5787910 PMID: 29417084 This study was conducted to compare the effect of low-dose isotretinoin with its conventional dose in patients with moderate and severe acne.This was a clinical trial conducted on 60 male and female patients with moderate and severe acne vulgaris. The patients were divided into two treatment …Read More »
Novel combination for the treatment of acne differentiated according to gender: a new step towards personalized treatment.
DOI: S0392-0488.18.05710-3 PMID: 29417793 The aim of this study is to evaluate efficacy and tolerability of a complete skin care line consisting of an oral supplement in two distinct formulations for males and females, and a topical cream device in the treatment of mild and moderate acne. Oral supplements contain biotin, …Read More »