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News: spironolactone


Spironolactone is primarily used to treat certain patients with hyperaldosteronism (the body produces too much aldosterone, a naturally occurring hormone); low potassium levels; heart failure; and in patients with edema (fluid retention) caused by various conditions, including liver, or kidney disease. It is also used alone or with other medications to treat high blood pressure. Spironolactone is in a class of medications called aldosterone receptor antagonists. It causes the kidneys to eliminate unneeded water and sodium from the body into the urine but reduces the loss of potassium from the body. Spironolactone is used, in some cases, used to treat adult acne.

Acne improved in most women treated with spironolactone

spironolactone acne treatment

Most of the postadolescent women with acne in a retrospective review of 400 patients treated over a 4-year period improved with spironolactone treatment, with a low rate of side effects, according to the authors. “The vast majority of our patients improved on spironolactone, despite many previously failing other acne treatments,” …

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Caution is key when prescribing spironolactone for adult acne

spironalacton acne

AT SDEF WOMEN’S & PEDIATRIC DERMATOLOGY SEMINAR   NEWPORT BEACH, CALIF. – While off-label use of spironolactone for the treatment of acne is quite common, it should be prescribed with special caution, advised Julie C. Harper, MD.  “The vast majority of you write this for acne,” Dr. Harper, a dermatologist …

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Combined OCs remain a good choice for teen acne

teen ance

MINNEAPOLIS – Whether a young female patient has a refractory flare of inflammatory acne, or has a condition that can predispose to androgen excess, using a hormonal approach can be an effective management tool for controlling adolescent acne. During a presentation at the annual meeting of the Society for Pediatric …

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How to use spironolactone safely for acne

Dr. Julie Harper of the University of Alabama in Birmingham

SAN FRANCISCO – The room was packed for a talk about spironolactone and acne at the annual meeting of the American Academy of Dermatology. Several dozen people were turned away at the door because there weren’t any seats left. Dermatologists have heard that the drug is a good option for …

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Oral Spironolactone Hailed for Acne in Women

Dr. Julie C. Harper Dermatology

The androgen receptor–blocker spironolactone is highly effective and safe but underused for the treatment of acne in women, according to Dr. Julie C. Harper. “The longer I’ve been in practice, the wider the age range where I use spironolactone as my drug of choice,” Dr. Harper said at the Hawaii …

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Spironolactone versus placebo for acne

Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne Plain language summary The evidence suggests a lack of evidence to show whether spironolactone can reduce hirsutism and acne. Hirsutism in women (excessive hair growth) is most often caused by an increased production of male hormones. Spironolactone (`Aldactone’ …

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