“As an intermediary step between topical antibiotics and oral isotretinoin, we propose that topical tretinoin may be effective in the management and reduction of rosacea symptoms,” Emily Forward, MD, of the University of Sydney, said at the meeting. There has been recent discussion regarding the use of low-dose isotretinoin in the treatment of rosacea, but safety with long-term use is an issue, she noted
She and her associates conducted a retrospective study of 25 patients with mild to severe rosacea who were treated with topical tretinoin 0.05% as monotherapy. They were also counseled on the use of sunscreen and moisturizer. They were followed up for a mean of 6 months (range 2-24 months).