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Clinical and laboratory studies on treatment with 20% azelaic acid cream for acne.

PMID: 2528256

In a series of investigations using 20% azelaic acid cream as a therapy for acne, it was found that the treatment, compared with its placebo, significantly reduced inflamed lesions after 1 month and non-inflamed lesions after 2 months. No changes in sebum excretion rate occurred, but a significant reduction, 15.9 to 10.5%, of free fatty acids of skin surface lipid was detected after 1 month. The follicular Micrococaceae density was significantly reduced after 1 month, and after 2 months there was a significant reduction in follicular Propionibacterium spp density. The final reductions were 2,500 and 44 fold, respectively.

Cunliffe WJ,  Holland KT

About Dr. J. Kim

Dr Kim developed (and is continuing to develop) dermatology research news as we way from dermatologists to stay on top of the latest advances in the field of dermatology.

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