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What is new in the pathophysiology of acne, an overview.

DOI: jdv.14374  PMID: 28805938   Acne is a chronic inflammatory disease of the pilosebaceous unit. Its pathophysiology includes hyperseborrhoea, abnormal follicular keratinization and Propionibacterium acnes proliferation in the pilosebaceous unit. Recent research has shed some new light on the involvement of the sebaceous gland, as well as on the pro-inflammatory activity of …

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Fragility of epidermis: acne and post-procedure lesional skin.

DOI: jdv.14410  PMID: 28805934   ‘Fragile skin’, or skin with lower resistance to aggressors, can be broadly classified into four causal categories: constitutional (age-dependent or associated with specific vulnerable locations on the body, e.g. eyelids), pathological (related to disease), circumstantial (related to environmental or internal factors, e.g. stress) and iatrogenic (caused by …

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Synchronizing Pharmacotherapy in Acne with Review of Clinical Care.

DOI: ijd.IJD_41_17  PMCID: PMC5527713  PMID: 28794543   Acne is a chronic inflammatory skin disease that involves the pathogenesis of four major factors, such as androgen-induced increased sebum secretion, altered keratinization, colonization of Propionibacterium acnes, and inflammation. Several acne mono-treatment and combination treatment regimens are available and prescribed in the Indian market, ranging from …

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Non-antibiotic Isotretinoin Treatment Differentially Controls Propionibacterium acnes on Skin of Acne Patients.

DOI: fmicb.2017.01381  PMCID: PMC5524737  PMID: 28790988   Emergence and potential transfer of antibiotic resistance in skin microorganisms is of current concern in medicine especially in dermatology contexts where long term treatment with antibiotics is common. Remarkably, non-antibiotic therapy in the form of isotretinoin – a non-antimicrobial retinoid is effective at reducing or eradicating …

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Wide range of age of onset and low referral rates to psychiatry in a large cohort of acne excoriée at a Swiss tertiary hospital.

DOI: 09546634.2017.1364693  PMID: 28784003   Repetitive skin manipulation is the key symptom in skin picking disorder (SPD), or acne excoriée des jeunes filles Brocq. The diagnostic and statistical manual of mental disorders (DSM-5) has recognized SPD as an independent disease, namely an obsessive-compulsive disorder. Thus, psychiatric treatment is indicated. Therefore, in a …

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Severe Acne Inversa – Dermatosurgical Approach in a Bulgarian Patient.

DOI: oamjms.2017.144  PMCID: PMC5535690  PMID: 28785365   We present a 55-year-old male patient – a smoker, admitted to a Medical Institute of MVR (Ministry of the interior, Sofia, Bulgaria), on occasion of pain and swellings, located in the area of both axillae, accompanied by purulent discharge, with bloody admixtures. Bilateral localised cystic rose …

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Skin microneedling plus Platelet-Rich Plasma versus skin microneedling alone in the treatment of atrophic post acne scars: a split face comparative study.

DOI: 09546634.2017.1365111  PMID: 28782384   Acne scarring is a permanent disfiguring sequel, which can take varied morphological forms. Many therapeutic measures have been performed to improve acne scarring such as microneedling. Our objective is to evaluate the efficacy and safety of microneedling alone versus microneedling in combined with platelet rich plasma in …

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