Recent Posts

Olumacostat Glasaretil, a Promising Topical Sebum-Suppressing Agent that Affects All Major Pathogenic Factors of Acne Vulgaris.

DOI: j.jid.2017.01.026  PMID: 28647025   Hunt et al. show that olumacostat glasaretil, an inhibitor of acetyl coenzyme A carboxylase, reduces saturated and monounsaturated fatty acyl chains in sebaceous lipids. Topical olumacostat glasaretil application decreases hamster ear sebaceous gland size and shows efficacy in treating patients with acne vulgaris. Olumacostat glasaretil-mediated sebum suppression may …

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Development and validation of IHS4, a novel dynamic scoring system to assess hidradenitis suppurativa/acne inversa severity.

DOI: bjd.15748  PMID: 28636793   A validated tool for the dynamic severity assessment of hidradenitis suppurativa (HS) is lacking. The aim of this study was to develop and validate such a novel scoring system. Zouboulis CC,  Tzellos T,  Kyrgidis A,  Jemec GBE,  Bechara FG,  Giamarellos-Bourboulis EJ,  Ingram JR,  Kanni T,  Karagiannidis I,  Martorell A,  Matusiak Ł,  Pinter A,  Prens EP,  Presser D,  Schneider-Burrus S,  von Stebut E,  Szepietowski …

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